Hydroxy Methionine Calcium MHA-Ca SUSTAR
Product Information
Chemical Name: Calcium Salt of 2-Hydroxy-4-Methylthiobutyric Acid
Molecular formula: (CH3SCH2CHOHCOO)2Ca
Molecular weight: 338.45
CAS No.: 4857-44-7
Appearance: White, light gray, or grayish-brown powder or granules, with a characteristic fishy odor
Physicochemical Specifications
|
Item |
Indicator |
|
Calcium Hydroxy Methionine, (CH3SCH2CHOHCOO)2Ca, % |
≥ 95.0 |
|
Methionine Hydroxy Analogue, % |
≥ 84.0 |
|
Ca2+, (%) |
11.0%~15.0% |
|
Total arsenic(subject to As), mg/kg |
≤ 2.0 |
|
Pb (subject to Pb), mg/kg |
≤ 20 |
|
Water content, % |
≤ 1.0 |
|
Fineness (425μm pass rate (40 mesh)), % |
≥ 95.0 |
Product Efficacy
1) Provides an efficient source of methionine
Hydroxy methionine calcium is a methionine analog that can be rapidly converted into L-methionine in animals, participating in protein synthesis.
2) Promotes feather, skin, and hoof health
Methionine is involved in keratin synthesis and is essential for the growth of keratinized tissues such as feathers in poultry and hooves in pigs.
3) Improves formulation flexibility and stability
Compared with DL-methionine, MHA-Ca is more stable, less hygroscopic, and resistant to caking, making it easier to store and mix.
4) Enhances immunity and antioxidant capacity
As a sulfur-containing amino acid, it participates in the synthesis of antioxidants such as glutathione (GSH), helping eliminate free radicals and improving stress resistance.
Product Application
1） Broiler chickens
Studies have shown that under heat stress conditions at 32 °C, the calcium salt of methionine hydroxy analog (HMTBa-Ca) improves feed intake, average daily gain, and muscle growth in broilers more effectively than DL-methionine (DLM). At the same time, it significantly enhances antioxidant capacity, reduces free radical levels, and improves redox status, thereby demonstrating superior performance in promoting production efficiency and alleviating oxidative stress.
Note: DLM refers to DL-methionine, and HMTBa-Ca refers to the calcium salt of hydroxy methionine analog. Different letters following data in the same column indicate significant differences among treatment groups (P < 0.05).
| Group | Final Body Weight (kg) | Average Daily Gain (g) | Average Daily Feed Intake (g) | Feed Conversion Ratio |
|
0.1%DLM |
2.25 ± 0.13a |
53. 61 ± 2. 99a |
122. 40 ± 4. 06a |
2.29 ± 0. 17b |
|
0.2%DLM |
2.37 ± 0. 14ab |
56. 41 ± 3. 38ab |
128. 24 ± 4. 22b |
2. 28 ± 0. 19b |
|
0.3%DLM |
2.39 ± 0. 15ab |
56. 85 ± 3. 63ab |
122. 65 ± 4. 83a |
2. 16 ± 0.11b |
|
0.1%HMTB-Ca |
2.38 ± 0. 18ab |
56. 61 ± 4. 22ab |
123. 16 ± 7. 07a |
2. 18 ± 0. 10b |
|
0.2%HMTB-Ca |
2.44 ± 0. 13b |
58. 01 ± 3. 03b |
130. 80 ± 4. 44b |
2. 26 ± 0. 17b |
|
0.3%HMTB-Ca |
2.57 ± 0. 11c |
61. 12 ± 2. 68c |
124. 93 ± 4. 92a |
2. 04 ± 0. 17a |
2） Pigs
Studies have found that supplementing piglet diets with one-eighth of DL-2-hydroxy-4-(methylthio)butanoic acid calcium (HMTBa-Ca) or with 65% of the dosage of DL-methionine (DLM) produced comparable improvements in growth performance, both significantly superior to methionine-deficient diets. No differences were observed among treatment groups in feed intake or mortality rate.
Table 1 Growth performance response to DL-methionine and DL-2 hydroxy-4-methylthio-butyrate acidfed at a ratio of 65:100 in nursery pigs
|
Variable |
Met-deficient |
HMTBCa |
65DLM |
SEM |
ANOVA, P- value |
|
BW, kg |
22.77b |
25.15a |
25.37a |
0.299 |
<0.001 |
|
ADG, g/d |
628b |
655a |
659a |
8.16 |
0.019 |
|
ADFl, g/d |
995 |
971 |
1010 |
14.00 |
0.164 |
|
G:F,g/g |
0.60b |
0.67a |
0.66a |
0.003 |
<0.001 |
|
Mortality,% |
0.00 |
0.00 |
0.06 |
0.036 |
0.376 |
1） Ruminants
In Holstein dairy cows, daily supplementation with 400 g of calcium salts of fatty acids and hydroxy methionine calcium significantly increased milk yield and lactose production. In primiparous cows, it also markedly improved reproductive performance, including higher conception rates and shorter calving intervals, without affecting body condition or body weight.
Table 2 Milk fat, protein and lactose yields (kg/day) and milk composition (g/kg) for cows receiving the control diet (C) or the lipid and methionine-supplemented diet (S)
|
Week of lactation |
C |
S |
S.E. |
|
|
Milk yield |
2-12 |
29.54a |
30.71b |
0.34 |
|
13-20 |
27.45c |
28.86d |
0.32 |
|
|
Fat yield |
2-12 |
1.17 |
1.19 |
0.01 |
|
13-20 |
1.10 |
1.10 |
0.01 |
|
|
Protein yield |
2-12 |
0.98 |
0.99 |
0.01 |
|
13-20 |
0.95 |
0.95 |
0.0 |
|
|
Lactose yield |
2-12 |
1.37c |
1.43d |
0.01 |
|
13-20 |
1.29c |
1.38d |
0.01 |
|
|
Fat concentration |
2-12 |
40.73 |
40.19 |
0.25 |
|
13-20 |
40.48c |
38.40d |
0.30 |
|
|
Protein concentration |
2-12 |
33.84c |
32.84d |
0.09 |
|
13-20 |
34.60c |
33.02d |
0.09 |
|
|
Lactose concentration |
2-12 |
46.36 |
46.36 |
0.08 |
|
13-20 |
6.71 |
46.76 |
0.09 |
|
Mean values with different superscripts within rows, are significantly different a,b(P < 0·05); c,d(P < 0·01).
Top Choice of International Grop
Sustar group has decades-long partnership with CP Group, Cargill, DSM, ADM,Deheus ,Nutreco,New Hope ,Haid,Tongwei and some other TOP 100 big feed company.
Our Superiority
A Reliable Partner
Research and development capabilities
Integrating the talents of the team to build Lanzhi Institute of Biology
In order to promote and influence the development of livestock industry at home and abroad, Xuzhou Animal Nutrition Institute , Tongshan District Government, Sichuan Agricultural University and Jiangsu Sustar, the four sides established Xuzhou Lianzhi Biotechnology Research Institute in December 2019.
Professor Yu Bing of Animal Nutrition Research Institute of Sichuan Agricultural University served as the dean, Professor Zheng Ping and Professor Tong Gaogao served as the deputy dean. Many professors of Animal Nutrition Research Institute of Sichuan Agricultural University helped the expert team to accelerate the transformation of scientific and technological achievements in the animal husbandry industry and promote the development of the industry.
As a member of the National Technical Committee for Standardization of Feed Industry and the winner of China Standard Innovation Contribution Award, Sustar has participated in drafting or revising 13 national or industrial product standards and 1 method standard since 1997.
Sustar has passed the ISO9001 and ISO22000 system certification FAMI-QS product certification, obtained 2 invention patents, 13 utility model patents, accepted 60 patents, and passed the "Standardization of intellectual property management system", and was recognized as a national-level new high-tech enterprise.
Our premixed feed production line and drying equipment are in the leading position in the industry. Sustar has high performance liquid chromatograph, atomic absorption spectrophotometer, ultraviolet and visible spectrophotometer, atomic fluorescence spectrophotometer and other major testing instruments, complete and advanced configuration.
We has more than 30 animal nutritionists, animal veterinarians, chemical analysts, equipment engineers and senior professionals in feed processing, research and development, laboratory testing, to provide customers with a full range of services from formula development, product production, inspection, testing, product program integration and application and so on.
Quality inspection
We provide test reports for each batch of our products, such as heavy metals and microbial residues. Each batch of dioxins and PCBS complies with EU standards. To ensure safety and compliance.
Assist customers to complete the regulatory compliance of feed additives in different countries, such as the registration and filing in the EU, USA, South America, Middle East and other markets.
Production Capacity
Main product production capacity
Copper sulfate-15,000 tons/year
TBCC -6,000 tons/year
TBZC -6,000 tons/year
Potassium chloride -7,000 tons/year
Glycine chelate series -7,000 tons/year
Small peptide chelate series-3,000 tons/year
Manganese sulfate -20,000 tons /year
Ferrous sulfate-20,000 tons/year
Zinc sulfate -20,000 tons/year
Premix (Vitamin/Minerals)-60,000 tons/year
More than 35 years history with five factory
Sustar group has five factories in China ,with annual capacity up to 200,000 tonns, covering totally 34,473 square meters，220 employees.And we’re an FAMI-QS/ISO/GMP certified company .
Customized Services
Customize Purity Level
Our company has a number of products have a wide variety of purity levels, especially to support our customers to do customized services, according to your needs. For example, our product DMPT is available in 98%, 80%, and 40% purity options; Chromium picolinate can be provided with Cr 2%-12%; and L-selenomethionine can be provided with Se 0.4%-5%.
Custom Packaging
According to your design requirements, you can customize the logo, size, shape, and pattern of the outer packaging
No one-size-fits-all formula? We tailor it for you!
We are well aware that there are differences in raw materials, farming patterns and management levels in different regions. Our technical service team can provide you with one to one formula customization service.
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