DMPT (Dimethyl-β-Propiothetin Hydrochloride) crystalline powder
DMPT (Dimethyl-β-Propiothetin Hydrochloride) crystalline powder
Dimethyl-β-Propiothetin Hydrochloride(referred to as DMPT)
DMPT (Dimethyl-β-Propiothetin Hydrochloride) crystalline powder
DMPT (Dimethyl-β-Propiothetin Hydrochloride) crystalline powder
Dimethyl-β-Propiothetin Hydrochloride(referred to as DMPT)

DMPT (Dimethyl-β-Propiothetin Hydrochloride) crystalline powder

  • English Name: DMPT (Dimethyl-β-Propiothetin Hydrochloride)
  • CAS:4337-33-1
  • Formula: C5H11SO2Cl
  • Molecular weight :170.66;
  • Appearance: White crystalline powder, soluble in water, deliquescent, easy to agglomerate (not affect the product effect).
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Physical and Chemical indicator:

Item

Indicator

III

DMPT(C5H11SO2Cl)                                      ≥

98

80

40

Loss of drying ,%                                       ≤

3.0

3.0

3.0

Residue on ignition,%                                   ≤

0.5

2.0

37

Arsenic (subject to As), mg / kg                         ≤

2

2

2

Pb (subject to Pb),  mg / kg                            ≤

4

4

4

Cd(subject to Cd),mg/kg                               ≤

0.5

0.5

0.5

Hg(subject to Hg),mg/kg                               ≤

0.1

0.1

0.1

Fineness(Passing rate W=900μm/20mesh test sieve)         ≥

95%

95%

95%

 

 

 

 

 

 

 

 

 

 

Purpose overview
DMPT is the best of a new generation of aquatic attractant, people use the phrase "fish biting the rock" to describe its enticing effect -- even it’s stone coated with this kind of thing, the fish will bite the stone. The most typical use is fishing bait, improve the palatability of the bite, make fish easily to bite.

The industrial use of DMPT is as a kind of eco-friendly feed additive to promote aquatic animals to intake feed and growth.

 

Production method of DMPT

Natural extraction method

The earliest DMPT is pure natural compound extracted from seaweed. Like marine algae, mollusc, euphausiacea, fish food chain contains natural DMPT.

 

Chemical synthesis method
Due to high cost and low purity of natural extraction method , and also not easily to the industrialization, artificial synthesis of DMPT has been made out to the large-scale application. Make chemical reaction of Dimethyl Sulfide and 3-Chloropropionic Acid in the solvent, and then become Dimethyl-Beta-Propiothetin Hydrochloride.


Differences between DMT and DMPT

Since there is a large gap between Dimethyl-Beta-Propiothetin (DMPT) and Dimethylthetin(DMT) in the terms of production cost, DMT has always been pretend to Dimethyl-Beta-Propiothetin (DMPT). It is necessary to make a distinction between them, the specific difference is as follows:

 

 

DMPT

DMT

1

Name

2,2-Dimethyl-β-propiothetin(Dimethylpropiothetin)

2,2-(Dimethylthetin)、(Sulfobetaine)

2

Abbreviation

DMPT、DMSP

DMT、DMSA

3

Molecular formula

C5H11ClO2S

C4H9ClO2S

4

Molecular 

structural 

formula 

   

5

Appearance

White crystalline powder

White needle-like or granular crystals

6

Smell

 

Faint smell of the sea

 

 

Slightly smelly

 

7

Existence form

It is widely found in nature and can be extracted from the Marine algae, Mollusc, Euphausiacea, wild Fish /Shrimp body

It is rarely found in nature, only in a few species of algae, or simply as a compound.

8

 

The flavor of aquaculture products

 

 

With a typical seafood flavor, the meat is tight and delicious.

Slightly smelly

9

Production cost

High

Low

10

 Attractant effect

Excellent ( proved by experimental data )

Normal

 

Mechanism of action of DMPT

1.Attractant effect

As an effective ligand for taste receptors:

Fish taste receptors interact with low molecular compounds containing(CH3)2S-and(CH3)2N-groups.DMPT, as a strong olfactory nerve stimulant, almost have the effect of inducing food and promoting food intake for all aquatic animals.

As a growth stimulant for aquatic animals, it can significantly promote the feeding behavior and growth upon various marine freshwater fishes, shrimps and crabs. The feeding stimulation effect of aquatic animals was 2.55 times higher than that of glutamine (which was known to be the best feeding stimulant for most freshwater fishes before DMPT).

2.High efficient methyl donor, growth promoting

Dimethyl-Beta-Propiothetin (DMPT) molecules (CH3) 2S groups have methyl donor function, could be effectively utilized by aquatic animals, and promote the secretion of digestive enzymes in the animal body, promote fish digestion and nutrient absorption , improve the utilization rate of the feed.

  • Improve the anti-stress ability, anti-osmotic pressure

Improve exercise capacity in aquatic animal and anti-stress ability (including hypoxia tolerance and high-temperature tolerance), improve the adaptability and survival rate of the juvenile fish. It can be used as osmotic pressure buffer, to improve the endurance of aquatic animals to a fast-changing osmotic pressure.

 

  • Has the similar role of ecdysone

DMPT has strong shelling activity, increasing speed of shelling in shrimp and crab, especially in the late period of shrimp and crab farming, the effect is more obvious.

Shelling and growth mechanism:

Crustaceans can synthesis DMPT by themselves. The current study show that for shrimp, DMPT is the new type of molting hormone analogues and also water-soluble , promote the growth rate through the promotion of shelling. DMPT is aquatic gustatory receptor ligand, could strongly stimulate the gustatory, olfactory nerve of aquatic animals, so as to increase up the feeding speed and feed consumption under the stress

  1. Hepatoprotective function

DMPT has liver protection function, not only can improve animal health and reduce visceral / body weight ratio but also improve the edibility of the aquatic animals.

  1. Improve the meat quality


DMPT can improve the meat quality, make freshwater species present seafood flavor, improve economic value.

7.Enhance the function of immune organs

DMPT also has a similar health care, antibacterial effects of “Allicin”.Anti-inflammatory factor expression was improved by activating[TOR/(S6 K1 and 4E-BP)] signaling

 

 

Efficacy


  1. DMPT is a naturally occurring sulfur-containing compound, is a new class of attractant out of the fourth generation of aquatic phagostimulant. The attractant effect of DMPT is as much as that of the choline chloride 1.25 times, 2.56 times of glycine betaine, 1.42 times of methyl-methionine, 1.56 times of glutamine. Glutamine is one of the best amino acid attractants, and DMPT is better than Glutamine. The study shows that DMPT is the effect best attractant.

    2. DMPT growth promoting effect is 2.5 times without the addition of semi-natural bait attractant.

    3. DMPT can improve meat quality, freshwater species has seafood flavor, so improve the economic value of freshwater species.

    4. DMPT is a shelling hormone-like substances, for shell of shrimp and other aquatic animals, it can significantly accelerate the shelling speed .

    5. DMPT as more economic protein source compared with fish meal, it provides larger formula space.

 

 

 

 

Usage dosage and residue problem

【Application】:

Freshwater fish: Tilapias, carp, crucian carp, eel, trout,etc.  

Marine fish: Salmon , large yellow croaker, sea bream, turbot and so on.

Crustaceans: shrimp, crab and so on.

【Dosage of usage】: g/t in the compound feed

Product Type

Common Aquatic Product/Fish

Common Aquatic Product /Shrimp and Crab

Special Aquatic Product

High-end Special Aquatic Product(such as sea cucumber,abalone,etc)

DMPT ≥98%

100-200

300-400

300-500

Fish fry stage:600-800

Middle and late stage:800-1500

DMPT ≥80%

120-250

350-500

     350-600

Fish fry stage:700-850

Middle and late stage: 950-1800

DMPT ≥40%

250-500

700-1000

     700- 1200

Fish fry stage:1400-1700

Middle and late stage:1900-3600

 

【Residual problem】: DMPT is a natural substance in aquatic animals, there is no residue problem, can be used for a long term.

【Package size】: 25kg/bag within three layers or fibre drum

【Packing】: Bag with double layers

【Storage methods】: sealed, stored in a cool, ventilated, dry place, avoid moisture.

【Period】: Two years.
【Content】: I Type ≥98.0%;II Type ≥ 80%;III Type ≥ 40%

【Note】 DMPT is acidic material, avoid direct contacting with alkaline additives.

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