Common Micronutrient Deficiencies in Marine fish Farming and Suggestions for Supplementation
1. Cobalt
Cobalt is required primarily for the synthesis of vitamin B12. Fish cannot synthesize B12 on their own, but cobalt is available to gut microbes.
Deficiency causes vitamin B12 deficiency to manifest as anemia, poor growth, and neurological dysfunction.
Cobalt is a core element of vitamin B12 involved in nucleic acid synthesis and erythropoiesis.
Products recommended for Cobalt supplementation
		    
			
		    
			2.Zinc
Zinc deficiency causes growth retardation, loss of appetite, and reduced feed conversion rate in fish.
Zinc deficiency in fish can cause skeletal deformities, curvature of the spine, and short stature.
Zinc deficiency can cause skin and fin lesions, fin rays rot, skin erosive lesions, and poor healing ability.
Fish with zinc deficiency have weakened immunity and are more susceptible to bacterial and parasitic infections.
Zinc is a component of various enzymes (e.g., carbonic anhydrase, alkaline phosphatase) involved in protein synthesis, cell division, and immune function.
Products recommended for Zinc supplementation
3. Selenium and VE(both synergistic effects, often considered together)
Selenium generally occurs in concert with VE deficiency, and selenium is a component of glutathione peroxidase, an enzyme that acts in conjunction with vitamin E to protect cell membranes from oxidative damage.
Fish with selenium deficiency can suffer from muscular dystrophy, muscle atrophy and weakness, commonly known as "white myopathy".
Se deficiency in fish results in exudative diathesis, where body fluids ooze into the interstitial space, resulting in edema.
Fish that lack selenium will have low immunity.
The importance of selenium for its powerful antioxidant effect protects cell membrane structural integrity.
Products recommended for Selenium and VE supplementation
		    
			
		    
			4.Copper
Fish can be anemic if copper is deficient. Copper is involved in iron absorption and utilization, and deficiency can lead to hypochromic anemia (pale skin and gills).
Copper deficiency in fish can cause bone deformities.
Fish with copper deficiency will have abnormal pigmentation: body color becomes light or abnormal.
Copper deficiency in fish can cause nervous system dysfunction: it occurs in extreme cases.
Copper is a core element in a variety of oxidases, such as cytochrome C oxidase, superoxide dismutase, and is involved in the respiratory chain, iron metabolism, and neurotransmitter synthesis.
Products recommended for Copper supplementation
5.Iodine
Fish will grow slowly if they lack iodine.
Fish iodine deficiency will reduce metabolic rate, mobility, poor appetite.
Iodine deficiency in fish can reduce reproductive ability and affect the quality and survival of offspring.
Iodine is an essential component of thyroid hormones (T3, T4) and regulates basal metabolic rate.
Products recommended for Iodine supplementation
		    
			
		    
			6.Manganese
Mn deficiency in fish results in skeletal deformities similar to Zn deficiency, which manifest as deformities of the spine and skull.
The growth of fish is inhibited by Mn deficiency.
Manganese deficiency in fish can cause metabolic disorders, affecting carbohydrate and lipid metabolism.
Mn deficiency in fish impairs reproduction and affects gonadal development and hatchability.
Manganese is an activator of important enzymes such as pyruvate carboxylase, involved in bone formation (mucopolysaccharide synthesis) and antioxidant defense.
Products recommended for Copper supplementation
7.Iron
Iron deficient fish become anemic and have reduced hemoglobin synthesis, resulting in pale gills and body color, dyspnea, and growth arrest.
Iron deficient fish have weakened immunity.
Iron is a key component of hemoglobin, myoglobin, and cytochrome and is responsible for oxygen transport and storage.
Products recommended for iron supplementation
		    
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